B Pharmacy interview exam for freshers – Part 1

B pharmacy job selection process

The job selection process of pharmaceutical companies is varies from company to company. Depend upon the company, you may appear for the B Pharmacy interview with or without writing an qualifying exam. Usually the reputed pharmaceutical companies conduct an qualifying exam before  selecting for interview. This qualifying exam will helps them to assure that the job aspirant is having minimum basic knowledge about the subject. As well as it helps to reduce the number of candidates appearing for interview.

For eg: 20 positions(Jobs) are available. But 300 candidates came to the interview location. Exam conducted for all the candidates; then top 60 or top 80 graduates selected for the interview based on the marks. Now the Job selection process is based on 1:3 or 1:4 ratio. Out of 3 or 4 candidates they offer job for one candidate.

Here we have given a model B Pharmacy interview exam paper for candidates who are looking for a b pharmacy fresher’s jobs in the pharmaceutical production plant and R&D. This exam contains only multiple choice questions or descriptive type questions or combinations of both.

b paharmacy interview exam

Answer all the questions (Each correct answer carries 2 marks)

  1. Write the chemical names?
    • a. Vitamin B6
    • b. Vitamin B12
  2. Write any two lubricants, which are used in tablets manufacturing?
  3. Write the abbreviations of IP and BP?
  4. What is friability test and how to calculate it?
  5. What are the steps involved in wet granulation process?
  6. Define API and explain it?
  7. Write any two types of formulations and explain it?
  8. Name any two sources of Vitamin C? Write any disease caused by vitamin c deficiency?
  9. What is oxymel?
  10. Expand the UHPLC, TLC, LVP and SVP?

Answers:

1)

  1. a) Vitamin B6- Pyridoxine
  2. b) Vitamin B12 – Cyanocobalamin

2) Commonly used lubricants are Talc, silica, Stearic acid and Magnesium stearate etc

3) IP full form Indian Pharmacopoeia

BP full form British Pharmacopoeia

4)  Friability test is conducted to know the physical strength of a tablet. It is the withstanding capacity of a tablet when it is on manufacturing and transportation.

It is calculated by using this formula

Friability =(Initial weight- Final weight)/Initial weight * 100

Initial weight in mg- before test

Final weight in mg- after completion of test

5) Following steps involved in the wet granulation process

  • Mixing
  • Drying
  • Dry screening
  • Fluid bed granulation

6) API is known as Active Pharmaceutical Ingredient. First and most important component of any formulation. There is no finished dose formulation is available without having an API.

7) Various types of formulations are available

Topical formulations:

This type of formulations are administered by local route, applied on the skin. The active ingredient in formulation does not enter into the systemic circulation.

e.g Topical creams

Parenteral formulations:

These formulations are administered by the parenteral route that in to blood. The ingredients in the formulation is directly enter in the blood. Bioavailability is high for this formulations.

ex: Intravenous Injections

8)  Oranges, Lemons and Tomotos are sources for vitamin C. Severe deficiency of vitamin C causes “scurvy” disease.

9)  Oxymel is a mixture of honey , water and vinegar.

10) UHPLC is known as Ultra High Performance Liquid Chromatography.

LVP is known as Large Volume Parenteral

SVP is known as Small Volume Parenteral

You can visit continuation of this questions and answers here.

This article was originally published on 29th dec 2017 and lastly updated on 16th april 2019.

Ethics committees-Clinical research in India.

Ethics committees-clinical research

In India, The concept of ethics committees were in 1980 by ICMR. Indian council of medical research (ICMR) provided the guidelines for the formation of Ethics committee.  Ethics committee (EC) formed as a group of members including medical or scientific professionals along with non-medical or non-scientific professionals/persons. EC can also be called as Review Board (RB). Ethics committee (EC) is designated for the purpose of protecting the rights, safety and well-being of the subjects (humans) participating in the clinical research. This board is responsible for reviewing and approving the clinical research study protocols or its amendments in an unbiased manner. No study will be conducted in humans anywhere in India without having prior Ethics committee approval.

Related: List of clinical trial registries in the world

Types of Ethics committees-clinical research:

Two types of Ethics Committees available in India. One is Institutional Ethics Committee, another one is Independent Ethics Committee. Sometimes both ethics committees written as “ICE” in the short form in India. But both ethics committees are completely different. Institutional Ethics Committee works similar to Institutional Review Board (IRB)in other countries.

ethics committees
Types of ethics committees in India

Institutional Ethics Committee:  

 It is formed by an institution that is a hospital/Research centre. It reviews the documents/protocols submitted by that institution for conducting clinical trials (BA/BE studies or Clinical trials).   It provides an unbiased opinion/approval about the proposed study from the research subjects point of view. It also perform ongoing review of the approved study at appropriate time intervals. Ethics committee consist of minimum of seven members and maximum of 15 members including chairman and member secretary. Ethics committee chairman should be from outside the institution.

Apart from the Ethics committee members, subject experts can also be invited for the EC meetings for their advice but they won’t voting rights for taking the decision about the proposed study protocol. It is mandatory to obtain EC approval letter before initiating the study.   

Related: Job opportunities after M pharm pharmacology

Independent Ethics Committees (IEC):

It is not a part of any institution or hospital or research centre. It is an independent body without having any relationship with the institution. It reviews the submitted protocols from institutions and give the approvals to conducting the studies. Most important point is, at present IEC can only give approvals to the Bio availability/ Bio equivalence (BA/BE) studies of approved drugs. Except from these two things, ICE will act as same as Institutional Ethics Committee.

At present, nearly 660 Ethics committees registered with Central Drugs Standard Control Organisation (CDSCO) in India. From this, approximately 530 are Institutional Ethics Committees and remaining (130) are Independent Ethics Committees.

Related: Download free pharmacology books

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