Pharma interview questions and answers – For Formulation production and R&D jobs:

Pharma interview notes:

We have already provided department wise pharma interview question and answers. Also provided qualifying exam papers for interview. Here we covered some more interview Q&A. these notes are also useful for interview. We are dedicated to provide some more interview questions as shown below in the near future. We also provide departmental wise interview notes continuously. Following Q&A are belongs to pharmaceutics which are useful for the production and R&D jobs.

What is corrosion?

It is a metal deterioration process. Due to chemical or chemical reactions or environmental interactions with surface metal, metal surface is gradually destructed. It is an unwanted process. Corrosion leads to machinery damage, product contamination and replacement of damaged machinery increase economic burden to the plant. Corrosion should be avoided by taking preventive measures.

What is passivation?

It is a procedure which makes the stainless steel more rust resistant by reducing the chemical reactivity of surface. Usually citric acid or nitric acid is used to do this process. It removes the free iron from the stainless steel surface. A protective oxide layer will be formed with inert in nature. This layer will less likely react with chemicals or air in the environment. If more layer is formed It will more resistant to corrosion less reactivity with chemicals.

What is the difference between dry bulb and wet bulb temperatures?

These are the temperatures useful to find the state of humid air.

The dry bulb temperature and wet bulb temperature is known as “air temperature” and “adiabatic saturation temperature” respectively.

Dry bulb temperature measured using a thermometer, bulb of the thermometer will be exposed freely in the air. While measuring the wet bulb temperature, bulb will be wrapped in a wet muslin cloth.

Pharma interview notes

What are azeotropes?

Azeotropes are also known as constant boiling mixtures. It is a mixture of liquids that act as a pure liquid having a constant boiling point. The boiling point may be higher or lower than individual component in the mixture’s boiling point. Azeotropes contains same composition of components in both liquid and vapour phase.

For eg:

water boiling temperature : 100 0C,

Ethanol boiling point : 78.3 0C

When a mixture of liquid composed 95% water and 5% ethanol by volume. This azeotrophic mixture will constantly boil at 78.2 0C. By using boiling method or simple distillation, we can not separate water and ethanol from this azeotrophic mixture.

If the mixture contains two liquids, is known as binary azeotropes. If it contains three liquids, it is known as ternary azeotropes.

Mention a few methods to enhance the solubility of poorly soluble drugs?

Various methods are used to enhance the drug solubility are as follows

– Particle size reduction

– Drug salt formation

– Solid dispersion

– Preparing Nano suspension

– Using surfactants

What is lyophilisation?

It is also known as freeze drying technique. In involves following steps

– Freezing: In this step, sterilised partially stoppered containers (drug+ excipients+ solvent) placed in the  freeze drying chamber.

-Primary drying(Sublimation): To sublimate water, pressure is reduced and heat increased. Ice crystals directly converted to vapour bypassing the liquid state. 95% water removed in this phase.

-Secondary drying (Desorption): Remaining bounded water removed in this phase. Temperature is increased more than the primary drying temperature. Then the vacuum is broken and filled with inert gas and sealed.   

This technique is used to preserve the biodegradable materials.

pharma interview notes which are not covered in the previous posts.
What is annealing?

Annealing is also known as slow freezing. When some compounds (ex. Amorphous compounds like mannitol) will not complete crystals. In this case, annealing is used. After forming the crystals, temperature is cycled. (Like -50 C to -30 C for few hours then back to -50 C). This process helps to form larger crystals.

What is osmosis?

It is a phenomenon. When dilute solution and concentrated solution separated by a semipermeable membrane. The  solvent passes from dilute solution to concentrated solution. This pressure is known as osmotic pressure.

Any fluid is injected into the body should be isotonic in nature. If hypertonic fluid injected into the body, it crenation of blood cells. If hypotonic fluid injected into the body, solvent passes in to blood cells causes haemolysis.

Mention a few solubility terms?

Very soluble- 1 part of solute soluble in less than 1 part of solvent

Freely soluble  -1 part of solute soluble in 1-10 parts of solvent

Soluble – 1 part of solute soluble in 10-30 parts of solvent

Sparingly soluble – 1 part of solute soluble in 30-100 parts of solvent

Slightly soluble – 1 part of solute soluble in 100 -1000 parts of solvent

Very slightly soluble – 1 part of solute soluble in 1000-10000 parts of solvent

Practically insoluble – 1 part of solute soluble in more than 10000 parts of solvent

Related: Clinical trials overview

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How to search pharma jobs- Part 1

Search pharma jobs

Based on my experience I am giving you the ways to search pharma jobs. After getting known this information, if you try genuinely, definitely you will get the job. Along with the information am also providing the required urls (uniform resource locator).  So that you can easily redirect to that pages or websites etc.

Methods to search pharma jobs can be divided as shown below.

A. Offline

B. Consultancies

C. Online

A. Offline- by direct contact

First of all we will go through the offline ways, it does not necessarily mean that you are not using help of internet, but it means the major work done through offline.

1. Reference:

In this method, you will approach your senior/relative/friend who are already working in the pharmaceutical industry. You provide them your resume, they will forward it to Human Resource (HR) department. You will get an interview opportunity, if you succeed, you will get the job. Story ends.

2. Resume distribution:

You have to take print outs of your resume. You have to go pharma industrial area (where you will find at least 10-20 pharmaceutical companies) and give your resume to front office/security office. If they have any urgent /bulk requirement with your qualification, you will get an interview call. If you are okay in interview you will get the job. Story ends.

Note:  This is a tedious process. If you want to try this method, definitely you should go to any pharma/biotech industrial area on bike only. If you go on public transport, you can’t give more than 5/6 resumes in a day because pharmaceutical companies/plants are located far away from its next pharma company usually (200-400 meters distance from its next company). Some companies will not allow you to submit the resume. This is the worst experience we have ever faced.

search pharma jobs
3. Campus interviews:

If your college is good and have relationships with the employers, your first interview call will be offered from your college itself. But this percentage is very less.

4. Job fair:

These are usually conducted by Non profit organisations or colleges. Any body can attend this job or sometimes registration should be done. Care should be taken in job fair if you are going to pay money. There is no specific job fair conducted for only pharma people point of view. Pharma specific job fairs are rare. Job fairs usually conducted on colleges or grounds on specified dates.

Related: Clinical trials overview

Due to large number of students, they don’t have time to take interview. They will take resumes or contact numbers. Most of the times, non-technical jobs will be recruited by this way. If you need a technical job suitable for your qualification, you have to try other methods.

Related: B pharmacy interview questions

B. Job Consultancies

This a paid method. Other discussed methods in this website are free to use and there is no involvement of third party person apart from you and employer. Choosing a good consultancy is important in this method. Job consultancies has it’s own advantages and disadvantages.

Advantages:

If you find a good trusted consultancy,

You need not to do anything to get an interview call.

You will have freedom to choose your interested department.

No need to strain more to get the reference.

Disadvantages:

You have to pay money

There is a chance of cheating (For ex. Consultancies should have an official tie up with the employers. Some consultancies have an individual tie-ups with HOD/HRs (this is not a correct way) to recruit the employees. If everything goes good, no problem. Other wise recruited employees will be treated as a back door employee).

Note: If you are preferring this method, try to pay major portion of the charged amount after receiving the first month salary only. If you get the salary on time like other employees, It is a sign of official confirmation from your employer.

Related: List of pharmaceutical companies in Hyderabad

This is the first part of how to search pharma jobs. Next part of ‘how to search pharma jobs’ discuss the online ways to search the pharma jobs.

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